- 일시: 2025년 7월 7일(월) 오전 10:30~
- 연사: Elisa Konofagou (Columbia University in the City of New York, NY, USA)
- 제목: Exploring The Ultrasound Of
The Future – Diagnostics, Therapeutics And Theranostics In Cardiovascular,
Cancer And Neurological Disease
- ABSTRACT
Ultrasound has been in the
clinic as an imaging and therapeutic modality for over four decades. In
imaging, elasticity imaging has been capable of expanding the role of
ultrasound imaging in the clinic by providing quantitative information on the
underlying mechanical properties. Emphases of this presentation will be given
on cardiovascular elasticity imaging techniques such as Myocardial
Elastography, Electromechanical Wave Imaging and Pulse Wave Imaging for the
characterization of mechanical and electrical cardiac properties and vascular
mechanical properties, respectively, based on the intrinsic pulsational
function of the heart and blood vessels. Elasticity imaging on preclinical and
clinical tumor characterization in the breast and pancreas using the radiation-force
technique of Harmonic Motion Imaging will also be presented. In therapeutics,
Focused Ultrasound (FUS) has been shown efficacious for applications spanning
from nerve stimulation to tumor ablation over the past six decades but clinical
translation has only been feasible during the last decade harnessing from MRI
thermometry. The lecture will focus on ultrasound-based monitoring by depicting
the associated stiffness change as well as on the more recent advances of
opening of the blood-brain barrier (BBB) for brain drug delivery towards the
treatment of Alzheimer’s, Parkinson’s and brain cancers well as central and
peripheral nervous system modulation.
- BIOGRAPHY
Elisa Konofagou is the Robert
and Margaret Hariri Professor of Biomedical Engineering and Professor of
Radiology and Neurosurgery as well as Director of the Ultrasound and Elasticity
Imaging Laboratory at Columbia University in New York City. Her main interests
are in the development of novel theranostic and therapeutic ultrasound methods
for the advancement of therapeutic ultrasound. Elisa has co-authored over 300
published articles in the aforementioned fields. Elisa is also an Elected
Member of the National Academy of Medicine (US), an Elected Fellow in the
International Society of Electrical and Electronic Engineering (IEEE), the
American Institute of Biological and Medical Engineering (AIMBE), and the
Acoustical Society of America (ASA).
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